Synchronous oligometastases in cervical cancer: a case report

Authors

  • Bothwell Takaingofa Guzha University of Cape Town http://orcid.org/0000-0002-3434-1677
  • Nondumiso Ngxola University of Cape Town
  • Tracey Adams University of Cape Town
  • Linda Rogers University of Cape Town
  • Nomonde Mbatani University of Cape Town
  • Hue-tsi Wu University of Cape Town
  • Nazia Fakie University of Cape Town
  • Vengesai Muzenda University of Cape Town
  • Lynette Denny University of Cape Town

Keywords:

cervical cancer, synchronous, metachronous, oligometastases, radical chemoradiation

Abstract

Incidence and mortality of cervical cancer in South Africa is still very high and 4-6% of women present with FIGO stage IVB disease. However, the management of oligometastatic cervical cancer is not well decribed in literature. Treatment of stage IVB cervical cancer is individualised, but it mainly involves palliative systemic chemotherapy with a median survival time of about ten months. There is a growing body of evidence showing that in women with low volume oligometastatic disease, curative doses of radiation therapy to the pelvis and metastatic sites with or without chemotherapy can prolong survival significantly. Since South Africa is one of the few countries in Africa with functional chemoradiation therapy facilities, there is a need to review this evidence and see if the standard of care has to be changed in women with oligometastatic cervical cancer. (Full text available online at www.medpharm.tandfonline.com/ojgo) South Afr J Gynaecol Oncol 2018; DOI: 10.1080/20742835.2018.1491139

Author Biographies

  • Bothwell Takaingofa Guzha, University of Cape Town
    Division of Gynaecology Oncology Department of Obstetrics and Gynaecology Groote Schuur Hospital Cape Town South Africa; and South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town South Africa
  • Nondumiso Ngxola, University of Cape Town
    Division of Gynaecology Oncology Department of Obstetrics and Gynaecology Groote Schuur Hospital Cape Town South Africa; and South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town South Africa
  • Tracey Adams, University of Cape Town
    Division of Gynaecology Oncology Department of Obstetrics and Gynaecology Groote Schuur Hospital Cape Town South Africa; and South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town South Africa
  • Linda Rogers, University of Cape Town
    Division of Gynaecology Oncology Department of Obstetrics and Gynaecology Groote Schuur Hospital Cape Town South Africa; and South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town South Africa
  • Nomonde Mbatani, University of Cape Town
    Division of Gynaecology Oncology Department of Obstetrics and Gynaecology Groote Schuur Hospital Cape Town South Africa; and South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town South Africa
  • Hue-tsi Wu, University of Cape Town
    South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town South Africa; and Division of Anatomical Pathology Groote Schuur Hospital National Health Laboratory Service Cape Town South Africa
  • Nazia Fakie, University of Cape Town
    South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town South Africa; and Department of Radiation Oncology Groote Schuur Hospital Cape Town South Africa
  • Vengesai Muzenda, University of Cape Town
    Department of Radiology Groote Schuur Hospital Cape Town South Africa
  • Lynette Denny, University of Cape Town
    Division of Gynaecology Oncology Department of Obstetrics and Gynaecology Groote Schuur Hospital Cape Town South Africa; and South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town South Africa

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Published

2018-11-20

Issue

Vol. 10 No. 2 (2018)

Section

Case Studies

License

South African Journal of Gynaecological Oncology (SAJGO) Copyright is held by South African Society of Gynaecologic Oncology (SASGO). Copyright of the articles is held by the authors. The work is licensed under a Creative Commons Attribution-Non-Commercial Works 4.0 South Africa License (CC BY NC). Material submitted for publication in the SAJGO is accepted provided it has not been published elsewhere. The SAJGO does not hold itself responsible for statements made by the authors. The opinions expressed in this publication are those of the authors. They do no purport to reflect the opinions or views of SASGO or its members.