Endometrial cancer with bone marrow metastases: a management dilemma

Authors

  • B T Guzha University of Cape Town
  • T Adams University of Cape Town
  • L Rogers University of Cape Town
  • N Mbatani University of Cape Town
  • H-T Wu University of Cape Town
  • N Fakie University of Cape Town
  • J Opie University of Cape Town
  • L A Denny University of Cape Town

Keywords:

infiltration, Grade 3 endometrioid endometrial cancer, leucoerythroblastic blood film, mortality, palliative care

Abstract

A case is presented of a 67-year-old woman referred to the authors’ institution with endometrioid endometrial cancer with a leucoerythroblastic blood film and marked thrombocytopenia. On further evaluation, it was confirmed that she had grade 3 endometrial cancer with bone marrow involvement (FIGO stage IVB). This is a rare complication of endometrial cancer and her marked thrombocytopenia severely limited her treatment options. (Full text available online at www.medpharm.tandfonline.com/ojgo) South Afr J Gynaecol Oncol 2017; DOI: 10.1080/20742835.2017.1394628

Author Biographies

  • B T Guzha, University of Cape Town
    Division of Gynaecology Oncology Department of Obstetrics and Gynaecology Groote Schuur Hospital; and South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town
  • T Adams, University of Cape Town
    Division of Gynaecology Oncology Department of Obstetrics and Gynaecology Groote Schuur Hospital; and South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town
  • L Rogers, University of Cape Town
    Division of Gynaecology Oncology Department of Obstetrics and Gynaecology Groote Schuur Hospital; and South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town
  • N Mbatani, University of Cape Town
    Division of Gynaecology Oncology Department of Obstetrics and Gynaecology Groote Schuur Hospital; and South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town
  • H-T Wu, University of Cape Town
    South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre; and Division of Anatomical Pathology Groote Schuur Hospital and the National Health Laboratory Service Cape Town
  • N Fakie, University of Cape Town
    South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre; and dDepartment of Radiation Oncology Groote Schuur Hospital Cape Town
  • J Opie, University of Cape Town
    Division of Haematology Pathology Groote Schuur Hospital National Health Laboratory Service and University of Cape Town Cape Town
  • L A Denny, University of Cape Town
    Division of Gynaecology Oncology Department of Obstetrics and Gynaecology Groote Schuur Hospital; and South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town

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Published

2017-12-04

Issue

Vol. 9 No. 2 (2017)

Section

Case Studies

License

South African Journal of Gynaecological Oncology (SAJGO) Copyright is held by South African Society of Gynaecologic Oncology (SASGO). Copyright of the articles is held by the authors. The work is licensed under a Creative Commons Attribution-Non-Commercial Works 4.0 South Africa License (CC BY NC). Material submitted for publication in the SAJGO is accepted provided it has not been published elsewhere. The SAJGO does not hold itself responsible for statements made by the authors. The opinions expressed in this publication are those of the authors. They do no purport to reflect the opinions or views of SASGO or its members.