Epithelioid trophoblastic tumour: a report of two cases

Authors

  • Moawia Mohammes Ali Elhassan University of Gezira
  • Hue-Tsi Wu University of Cape Town
  • Leon Van Wijk University of Cape Town

Keywords:

epithelioid trophoblalstic tumour, uterus, cancer, post-coital bleeding, dyspareunia

Abstract

An epithelioid trophoblalstic tumour (ETT) is an extremely rare form of gestational trophoblastic disease (GTD).1 Usually, patients are of child-bearing age with a prior gestation.2 The uterus is the most common site for an ETT.3 This tumour has the same clinical behaviour as that of a placental site trophblastic tumour, but the treatment options may differ. Histologically, an ETT is a distinct neoplasm whose cytological features and growth patterns mimic those of squamous cell carcinoma.3 An ETT does not appear to be as chemosensitive as other GTDs, making hysterectomy the treatment of choice in patients with disease confined to the uterus.3 This tumour may present a diagnostic challenge to the pathologist, while clinicians often face problems with treating this tumour because of its rarity. We describe two cases of an ETT occurring in two women, one aged 44 years and the other 42 years.

Author Biographies

  • Moawia Mohammes Ali Elhassan, University of Gezira
    FCRadOnc, MMedRadOnc Radiation Oncologist Department of Radiation Oncology National Cancer Institute University of Gezira PO Box 20
  • Hue-Tsi Wu, University of Cape Town
    FCPathAnat, MMed Senior Consultant Department of Anatomical Pathology University of Cape Town South Africa
  • Leon Van Wijk, University of Cape Town
    FFRAD(T) Senior Consultant Department of Radiation Oncology University of Cape Town South Africa

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Published

2014-09-05

Issue

Vol. 7 No. 1 (2015)

Section

Case Studies

License

South African Journal of Gynaecological Oncology (SAJGO) Copyright is held by South African Society of Gynaecologic Oncology (SASGO). Copyright of the articles is held by the authors. The work is licensed under a Creative Commons Attribution-Non-Commercial Works 4.0 South Africa License (CC BY NC). Material submitted for publication in the SAJGO is accepted provided it has not been published elsewhere. The SAJGO does not hold itself responsible for statements made by the authors. The opinions expressed in this publication are those of the authors. They do no purport to reflect the opinions or views of SASGO or its members.