Ovarian germ cell tumour and bleomycin-induced lung injury

Authors

  • P Barnardt Stellenbosch University
  • S Griffith-Richards Stellenbosch University

Keywords:

bleomycin, germ cell, lung toxicity, ovarian cancer

Abstract

Bleomycin, an antibiotic agent with antitumour activity, is an important drug in the management of many oncological malignancies such as lymphoma and germ cell tumours. These tumours are potentially curable and mostly affect young people. The potential side effects and long-term toxicities should be considered. The major limitation of bleomycin therapy is pulmonary toxicity and may be life threatening in about 10% of cases. This article reports a case of an ovarian mixed germ cell tumour, which presented with bleomycin associated pulmonary toxicity. (Full text available online at www.medpharm.tandfonline.com/ojgo) South Afr J Gynaecol Oncol 2018; DOI: 10.1080/20742835.2018.1479213

Author Biographies

  • P Barnardt, Stellenbosch University
    Department of Medical Imaging and Clinical Oncology (MICO) Stellenbosch University Stellenbosch South Africa
  • S Griffith-Richards, Stellenbosch University
    Department of Medical Imaging and Clinical Oncology (MICO) Stellenbosch University Stellenbosch South Africa

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Published

2018-11-20

Issue

Vol. 10 No. 2 (2018)

Section

Case Studies

License

South African Journal of Gynaecological Oncology (SAJGO) Copyright is held by South African Society of Gynaecologic Oncology (SASGO). Copyright of the articles is held by the authors. The work is licensed under a Creative Commons Attribution-Non-Commercial Works 4.0 South Africa License (CC BY NC). Material submitted for publication in the SAJGO is accepted provided it has not been published elsewhere. The SAJGO does not hold itself responsible for statements made by the authors. The opinions expressed in this publication are those of the authors. They do no purport to reflect the opinions or views of SASGO or its members.