Management of premalignant lesions of the cervix

Authors

  • BG Lindeque University of Pretoria

Keywords:

premalignant lesions, cervix

Abstract

It is accepted that high risk human papilloma virus (HPV) types are the carcinogens for cancer of the cervix. Cervical carcinogenesis is a slow process where cellular changes occur after integration of HPV DNA into the host genome. This dysplasia may revert to normal or may increase in severity over time and in a minority of patients may ultimately progress to invasive cervical carcinoma. For most patients caught in the process of cervical carcinogenesis the status will be that of noninvasive cancer and the diagnosis will be Cervical Intra-epithelial Neoplasia (CIN). This diagnosis creates a window of opportunity to manage the premalignant lesion and thus prevent further malignant progression.

Author Biography

  • BG Lindeque, University of Pretoria
    Professor and Head: Dept Obstetrics and GynaecologyUniversity of Pretoria

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Issue

Vol. 1 No. 2 (2009)

Section

Review Articles

License

South African Journal of Gynaecological Oncology (SAJGO) Copyright is held by South African Society of Gynaecologic Oncology (SASGO). Copyright of the articles is held by the authors. The work is licensed under a Creative Commons Attribution-Non-Commercial Works 4.0 South Africa License (CC BY NC). Material submitted for publication in the SAJGO is accepted provided it has not been published elsewhere. The SAJGO does not hold itself responsible for statements made by the authors. The opinions expressed in this publication are those of the authors. They do no purport to reflect the opinions or views of SASGO or its members.