Ovarian germ cell tumour and bleomycin-induced lung injury

  • P Barnardt Stellenbosch University
  • S Griffith-Richards Stellenbosch University
Keywords: bleomycin, germ cell, lung toxicity, ovarian cancer

Abstract

Bleomycin, an antibiotic agent with antitumour activity, is an important drug in the management of many oncological malignancies such as lymphoma and germ cell tumours. These tumours are potentially curable and mostly affect young people. The potential side effects and long-term toxicities should be considered. The major limitation of bleomycin therapy is pulmonary toxicity and may be life threatening in about 10% of cases. This article reports a case of an ovarian mixed germ cell tumour, which presented with bleomycin associated pulmonary toxicity. (Full text available online at www.medpharm.tandfonline.com/ojgo) South Afr J Gynaecol Oncol 2018; DOI: 10.1080/20742835.2018.1479213

Author Biographies

P Barnardt, Stellenbosch University
Department of Medical Imaging and Clinical Oncology (MICO) Stellenbosch University Stellenbosch South Africa
S Griffith-Richards, Stellenbosch University
Department of Medical Imaging and Clinical Oncology (MICO) Stellenbosch University Stellenbosch South Africa
Published
2018-11-20
Section
Case Studies