Synchronous oligometastases in cervical cancer: a case report

Bothwell Takaingofa Guzha University of Cape Town http://orcid.org/0000-0002-3434-1677
Nondumiso Ngxola University of Cape Town
Tracey Adams University of Cape Town
Linda Rogers University of Cape Town
Nomonde Mbatani University of Cape Town
Hue-tsi Wu University of Cape Town
Nazia Fakie University of Cape Town
Vengesai Muzenda University of Cape Town
Lynette Denny University of Cape Town

Keywords: cervical cancer, synchronous, metachronous, oligometastases, radical chemoradiation

Abstract

Incidence and mortality of cervical cancer in South Africa is still very high and 4-6% of women present with FIGO stage IVB disease. However, the management of oligometastatic cervical cancer is not well decribed in literature. Treatment of stage IVB cervical cancer is individualised, but it mainly involves palliative systemic chemotherapy with a median survival time of about ten months. There is a growing body of evidence showing that in women with low volume oligometastatic disease, curative doses of radiation therapy to the pelvis and metastatic sites with or without chemotherapy can prolong survival significantly. Since South Africa is one of the few countries in Africa with functional chemoradiation therapy facilities, there is a need to review this evidence and see if the standard of care has to be changed in women with oligometastatic cervical cancer. (Full text available online at www.medpharm.tandfonline.com/ojgo) South Afr J Gynaecol Oncol 2018; DOI: 10.1080/20742835.2018.1491139

Author Biographies

Bothwell Takaingofa Guzha, University of Cape Town

Division of Gynaecology Oncology Department of Obstetrics and Gynaecology Groote Schuur Hospital Cape Town South Africa; and South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town South Africa

Nondumiso Ngxola, University of Cape Town

Tracey Adams, University of Cape Town

Linda Rogers, University of Cape Town

Nomonde Mbatani, University of Cape Town

Hue-tsi Wu, University of Cape Town

South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town South Africa; and Division of Anatomical Pathology Groote Schuur Hospital National Health Laboratory Service Cape Town South Africa

Nazia Fakie, University of Cape Town

South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town South Africa; and Department of Radiation Oncology Groote Schuur Hospital Cape Town South Africa

Vengesai Muzenda, University of Cape Town

Department of Radiology Groote Schuur Hospital Cape Town South Africa

Lynette Denny, University of Cape Town

Published

2018-11-20

Issue

Vol 10 No 2 (2018)

Section

Case Studies

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