Endometrial cancer with bone marrow metastases: a management dilemma

  • B T Guzha University of Cape Town
  • T Adams University of Cape Town
  • L Rogers University of Cape Town
  • N Mbatani University of Cape Town
  • H-T Wu University of Cape Town
  • N Fakie University of Cape Town
  • J Opie University of Cape Town
  • L A Denny University of Cape Town
Keywords: infiltration, Grade 3 endometrioid endometrial cancer, leucoerythroblastic blood film, mortality, palliative care

Abstract

A case is presented of a 67-year-old woman referred to the authors’ institution with endometrioid endometrial cancer with a leucoerythroblastic blood film and marked thrombocytopenia. On further evaluation, it was confirmed that she had grade 3 endometrial cancer with bone marrow involvement (FIGO stage IVB). This is a rare complication of endometrial cancer and her marked thrombocytopenia severely limited her treatment options. (Full text available online at www.medpharm.tandfonline.com/ojgo) South Afr J Gynaecol Oncol 2017; DOI: 10.1080/20742835.2017.1394628

Author Biographies

B T Guzha, University of Cape Town
Division of Gynaecology Oncology Department of Obstetrics and Gynaecology Groote Schuur Hospital; and South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town
T Adams, University of Cape Town
Division of Gynaecology Oncology Department of Obstetrics and Gynaecology Groote Schuur Hospital; and South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town
L Rogers, University of Cape Town
Division of Gynaecology Oncology Department of Obstetrics and Gynaecology Groote Schuur Hospital; and South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town
N Mbatani, University of Cape Town
Division of Gynaecology Oncology Department of Obstetrics and Gynaecology Groote Schuur Hospital; and South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town
H-T Wu, University of Cape Town
South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre; and Division of Anatomical Pathology Groote Schuur Hospital and the National Health Laboratory Service Cape Town
N Fakie, University of Cape Town
South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre; and dDepartment of Radiation Oncology Groote Schuur Hospital Cape Town
J Opie, University of Cape Town
Division of Haematology Pathology Groote Schuur Hospital National Health Laboratory Service and University of Cape Town Cape Town
L A Denny, University of Cape Town
Division of Gynaecology Oncology Department of Obstetrics and Gynaecology Groote Schuur Hospital; and South African Medical Research Council (SAMRC)/University of Cape Town (UCT) Gynaecological Cancer Research Centre Cape Town
Published
2017-12-04
Section
Case Studies